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Health Economics and Payer Evidence Director, Oncology


Gaithersburg, US or Cambridge, UK

Application Deadline

About Astrazeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases.


We’re all here to make an impact – to achieve our bold ambition of eliminating cancer as a cause of death.

In the Oncology Business Unit we relentlessly follow the science, challenging the status quo to deliver more effective treatments to patients in need. Our commitment means we purposefully push back the limits of knowledge to change the practice of medicine. To ensure no patient is left behind, no matter what stage of disease.


Join a highly valued, strategic team that is fundamental in realising the potential of our life-changing medicines. It’s through our work that AstraZeneca is able to ensure the right access is provided to our transformative medicines.

Working with new drugs, new digital approaches and ever-changing environments, it’s crucial that we remain flexible and on top of the detail. Running, thinking and acting fast to make smart decisions and get the right medicines to patients at the right time.

We lead the way for the industry with our pioneering valued-based agreements and Innovative Value Strategy solutions. It’s our determination and unwavering belief in the power of our medicines, and the science sitting behind them, that drives us to ensure their value is realised.

Inspired by our people, patients and pipeline, we work cross-functionally to leverage our shared skills, knowledge and entrepreneurial spirit to change the way medicines are assessed and perceived, and turn ambitions into reality.

We’re pioneering Market Access innovations: this is the place to unlock opportunities and feed our love for the challenge. United by an unrivalled passion for patients and science and always performing at the top of our game.


The HEPE Director will lead a team (player-coach model) and the global health economic and payer evidence strategy and plan, across the IO GI, GU and Women’s cancer indications. This includes:

The successful candidate will work closely with the GI and GU Pricing and Market Access Directors, the HEPE team across GI/GU and Womens cancer indications, the Simulation and Analytics team, the IVS team, our marketing companies (local affiliates), and cross functionally – Globally and Regionally, with an expectation that they will make impact into strategic discussions across R&D, medical and commercial.

  • Collaborate with cross functional R&D, commercial, regional and country teams to develop, launch and commercialise AstraZeneca Oncology medicines.
  • High quality health economics and payer evidence input into pharmaceutical development projects, payer evidence strategy and plans, and market access & pricing strategies
  • Matrix manage a cross functional team to support the development of payer strategy and evidence including payer statistical analyses, patient reported outcomes, health economics and real-world evidence.
  • Delivery of health economics and payer evidence related activities, and contribute to work streams, to ensure optimal access of our life changing medicines to patients
  • Deliver clear, customer-focused and robust Global Reimbursement Dossiers (GRDs)
  • Ensure target product profiles and target claims can meet payer needs and necessary supporting evidence is developed.
  • Apply your knowledge to support decision-making processes, value demonstration and commercialization of products including through Health Technology Assessment (HTA).
  • Advocate and champion the need for scientifically sound trial and non-trial data (including RWE, economic modelling, meta-analyses, observational studies, and PRO approaches).
  • Contribute and lead payer evidence discussions in relevant cross-functional team meetings – eg GPT (Global Product Team), IBT (Integrated Brand Team), RSST (Regulatory Submission Strategy Team), RWE Strategy team
  • Contribute to GI Tumour Strategy plan from a payer evidence perspective
  • Collaborate with marketing companies/local affiliates in preparing evidence that satisfies their local payer requirements
  • Contribute to peer reviewed scientific publications, as well as effective communication of complex ideas for use with both payers and other stakeholders
  • Participate in external health economics and payer evidence departmental activities via technical presentations, committee membership, publication reviews, and other similar activities
  • Interact with HTA authorities and advisors/key external experts in preparing materials for scientific advice or reimbursement submissions

Essential Requirements

  • Graduate degree in biomedical science, business, quantitative disciplines or economics.
  • Oncology therapy area experience
  • Local or global launch experience, having worked at a senior level within a health economic consultancy or several years in a pharmaceutical company (either at a marketing company/local affiliate or global level).
  • Ability to communicate technical matters in a clear, compelling and impactful way with others via a range of media (e.g. face to face, teleconferences, video conferences, formal presentations, strong scientific writing for reports, analysis plans and emails).

Desirable Requirements

  • Global payer launch experience and global payer evidence development experience.
  • Team management experience
  • Post-graduate degree in health economics or a related quantitative discipline

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